Paul Anthony Macary,Soh Ha Chan,Brendon John Hanson
申请号:
US13510690
公开号:
US20120294874A1
申请日:
2010.11.18
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Methods are provided for producing T cell receptor (TCR) like antibodies that recognize peptides displayed in the context of HLA molecules. Antibodies produced by methods provided herein have the specificity of a TCR and can be used as therapeutic, diagnostic and research reagents. Also provided are TCR-like antibodies which recognize Epstein-Barr virus (EBV) peptides displayed in the context of HLA molecules and are useful for the detection and treatment of EBV and EBV-linked diseases.