WANG, XIAODONG,LIU, JING,ZHANG, WEIHE,FRYE, STEPHEN,KIREEV, DMITRI
申请号：
EP12839069
公开号：
EP2763988A4
申请日:
2012.10.01
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemia (ALL) cells and a potential cause of ALL chemoresistance. Hence, we investigated whether the development of small molecule Mer inhibitors was possible. A first aspect of the present invention is a compound (sometimes referred to as an &ldquo；active compound&rdquo； herein) of Formula I, IA, or IB.
