Methods of treating developmental disorders such as Angelman syndrome, Fragile X syndrome, Fragile X-associated tremor/ataxia syndrome (FXTAS), Autistic Spectrum Disorder, Autism, Asperger’s syndrome, pervasive developmental disorder, Childhood Disintegrative Disorder, Rett syndrome, Lanau-Kleffner Syndrome, Prader-Willi Syndrome, Tardive Dyskinesia, and/or Williams Syndrome with gaboxadol or a pharmaceutically acceptable salt thereof are provided. The methods provide therapeutic compositions that may be used to improve one or more symptoms of the developmental disorder.本發明提供以加波沙朵或其醫藥學上可接受之鹽治療發育障礙(諸如安格曼症候群、脆弱X染色體症候群、脆弱X染色體相關震顫/共濟失調症候群(FXTAS)、自閉症系列障礙、自閉症、亞斯伯格症候群、廣泛性發育障礙、兒童期崩解症、瑞特氏症候群、拉諾-克勒夫納症候群、普瑞德-威利症候群、遲發性運動障礙,及/或威廉氏症候群)之方法。該等方法提供可用於改良發育障礙之一或多種症狀之治療性組合物。