University of Florida Research Foundation, Inc.;Bartelmez, Stephen H.
发明人:
申请号:
EP09723461.1
公开号:
EP2271748B1
申请日:
2009.03.19
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Disclosed herein are methods of enhancing repair of vascular lesions involving the administration of cells in which TGF-&bgr; expression and/or activity has been transiently blocked. Other methods involve the administration of a TGF-&bgr; blocking agent to a subject who has a vascular lesion or is at risk of developing a vascular lesion. Alternatively, a TGF-&bgr; blocking agent and treated cells are co-administered to a subject in need thereof.