David M. Center;William W. Cruikshank;Hardy Kornfeld
发明人:
David M. Center,William W. Cruikshank,Hardy Kornfeld
申请号：
US13424692
公开号：
US20120213790A1
申请日:
2012.03.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention has found that a series of peptides having sequences that substantially correspond to specific regions of the C-terminus of IL-16 can inhibit the activity of IL-16. The present invention has demonstrated that such IL-16-inhibiting peptides can be as short as 4 amino acid in length. Based on these discoveries, the present invention provides IL-16 antagonist peptides and the use thereof for the treatment of IL-16 mediated disorders such as certain inflammatory diseases.
