The present invention relates to a method of cleansing the colon using colon cleansing solutions, and compositions and kits associated therewith. The invention provides a colon cleansing solution comprising: a) 300 to 800 mmol per litre ascorbate anion provided by a mixture of (i) ascorbic acid and (ii) one or more salts of ascorbic acid； the components (i) and (ii) being present in a molar ratio of from 1:4.5 to 1:7.0； and b) 10 to 200 g per litre polyethylene glycol. The solution of the invention has a palatable taste. The particular ratio of ascorbic acid to salt of ascorbic acid enables the salty taste of ascorbate salt to be balanced by sourness from acid to a palatable extent, whilst at the same time not reducing the osmotic effect of the ascorbate component or making the solution too sour. The solution is highly effective as a colon cleansing solution when ingested in a lower volume than many prior art solutions, and it has a good tolerability profile. The invention also or alternatively provides non-therapeutic methods of cleaning the colon, use in the manufacture of a medicament for the treatment of constipation or faecal impaction, kits associated with, or making use of the solutions, and/or compositions for the preparation of the solutions.
