New ubiquitin ligase and its use

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专利权人:

国立大学法人愛媛大学

发明人:

東山 繁樹,井上 博文,大貫 秀隆

申请号：

JP2009277073

公开号：

JP5665213B2

申请日:

2009.12.04

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

<；P>；PROBLEM TO BE SOLVED: To provide a new ubiquitin ligase and its adapter components. <；P>；SOLUTION: There are disclosed: a ubiquitin ligase component comprising BAZF； a ubiquitin ligase component comprising BAZF and CUL3； a ubiquitin ligase including the components； a ubiquitin ligase controlling agent featured by including a substance for controlling the expression of BAZF； a Notch signal controlling agent featured by including any of these components, ubiquitin ligase and its controlling agents； or preventive or therapeutic agents for diseases caused by the abnormality of Notch signaling system. <；P>；COPYRIGHT: (C)2011,JPO&INPIT

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