A biological tissue interface system is disclosed which employs an electroactive polymer actuator to pivot a tissue interface portion which may be adapted to engage with neural tissue. The system comprises a base portion, an articulating portion having a proximal end attached to the base portion and a free distal end, and an actuator operably coupled to the articulating portion, driven by a conjugated polymer that changes dimension in response to an electric charge. The polymer applies a force to pivot the articulating portion, relative to the base portion, to engage tissue at the distal tissue interface. In neural interface applications, the articulating portion may comprise at least one conducting surface for neural communications, such as a microelectrode or a polymer.