A syringe for drug injection from a cartridge (26) has a hand-and- thumb operated plunger (4) that slides through a finger-hold (3) into a tubular body (1) which is attached to the finger-hold (3) by a bayonet connection between pins (17) of the finger-hold (3) and L-shape slots (15) of the tubular body (1). The bayonet connection is established by twisting the body (1) relative to the finger-hold (3) and this also engages tags (16) of the body (1) with slots (18) of the finger-hold (3) to enhance the attachment. A needle-guard sleeve (12) slides on the tubular body (1) between a retracted condition in which it is clear of the distal end (8) of the body (1) for needle-attachment, and a pre-use condition in which the needle (32) is shielded. After injection the sleeve (12) is pushed further forward over the needle (32) into a post- use condition, from which return to the earlier conditions is blocked. A syringe for drug injection from a cartridge Q6) has a hand-and- f hrrmlr.nFrAr.ed. plunger (4) that slides through a f inqer-hold (3 ) ullwlry vyv4sv into a tubul-ar body (1) which is attached to the f inger-hold (3 ) by a bayonet connection between pins (I7) of the finger-hold (3) and L-shape slots (15) of Lhe tubular body (1) The bayonet connection is established by twisting the body (1) relative to the finger-hold (3) and this also engages tags (16) of the body (1) with slots (18) cf the finger-hold (3) to enhance the attachment A needle-guard sleeve ]2) slides on the tubular body (1) between a retracted condition in which it is cl-ear of the distal end (B ) of Lhe body (1) for needle-attachment, and a pre-use condition in which the need.le G2) is shielded Af ter injection the sleeve (L2) is pushed further forward over the needle,32) into a post- use condition, from which return to the earlier conditions is r-l nnJ:od vIvvJLvs.Cette invention concerne une seringue, pour linjection de médicaments à partir dune cartouche (26), comportant un piston (4) mû par une act