CHANG BETTY,BALASUBRAMANIAN SRIRAM,CROWLEY RICHARD,KUO HSU-PING,HALL BRETT,SASSER A KATE,SCHAFFER MICHAEL,DAVIS CUC,CASNEUF TINEKE,VERSELE MATTHIAS,LIGTENBERG WILLEM
申请号:
IN8730/DELNP/2015
公开号:
IN2015DN08730A
申请日:
2015.09.23
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
Combinations of Bruton s tyrosine kinase (Btk) inhibitors e.g. 1 ((R) 3 (4 amino phenoxyphenyl) 1 H pyrazolo [3 4 d]pyrimidin 1 yl)piperidin 1 yl)prop 2 en 1 one with a second anticancer agent are provided. Also provided are methods of treating cancers and autoimmune disorders by administering combinations of Bruton s tyrosine kinase (Btk) inhibitors e.g. 1 ((R) 3 (4 amino 3 (4 phenoxyphenyl) 1H pyrazolo[3 4 d]pyrimidin 1 yl)piperidin 1 yl)prop 2 en 1 one and second anticancer agents.