RAMMENSEE, Hans-Georg,SCHUSTER, Heiko,PEPER, Janet,WAGNER, Philipp,RÖHLE, Kevin
申请号:
CL2019002093
公开号:
CL2019002093A1
申请日:
2019.07.26
申请国别(地区):
CL
年份:
2019
代理人:
摘要:
T. The current invention of lt; P gt; oacute; n refers to P amp; eacute; pties, prot amp; Iacute; NAS, amp; Aacute; cidos nuclei and C amp; eacute; Lulas for all immunotherapy amp; eacute; props of utilici amp; oacute; n EN M amp; eacute. In particular, current inventions and amp; oacute; n refer to immunity to C amp; Aacute; NCER. The present invention; oacute; n also refers to EP amp; Iacute; topos pept amp; Iacute; dics for lymphocytic diseases related to tumors, either alone or in combination; oacute; N and other P amp; eacute; baptisms are related to tumors, for example,They can be used as a positive principle: pharmacology and amperometric; eacute; a tool for vaccine composition, whose purpose is to stimulate antitumor immune response, or to stimulate the subsequent emergence of pre living lymphocyte T; eacute; s ser amp; Aacute; for referral to patients. P amp; eacute; impregnation combined with mol amp; eacute; butt of MHC complex,O P eacute; ptidos, tambi eacute; n can be antibody targets, soluble lymphocyte receptors and other mol eacute; uni amp; butt; oacute; n lt; / P gt;<;p>;LA PRESENTE INVENCIÓ;N SE REFIERE A PÉ;PTIDOS, PROTEÍ;NAS, Á;CIDOS NUCLEICOS Y CÉ;LULAS DESTINADOS A LA UTILIZACIÓ;N EN MÉ;TODOS INMUNOTERAPÉ;UTICOS. EN PARTICULAR, LA PRESENTE INVENCIÓ;N SE REFIERE A LA INMUNOTERAPIA CONTRA EL CÁ;NCER. LA PRESENTE INVENCIÓ;N SE REFIERE ASIMISMO A EPÍ;TOPOS PEPTÍ;DICOS PARA LINFOCITOS T ASOCIADOS A TUMORES, SOLOS O EN COMBINACIÓ;N CON OTROS PÉ;PTIDOS ASOCIADOS A TUMORES QUE, POR EJEMPLO, PUEDEN SERVIR COMO PRINCIPIOS ACTIVOS FARMACÉ;UTICOS EN COMPOSICIONES VACUNALES DESTINADAS A ESTIMULAR RESPUESTAS INMUNITARIAS ANTITUMORALES, O A ESTIMULAR EX VIVO LINFOCITOS T QUE DESPUÉ;S SERÁ;N TRANSFERIDOS A LOS PACIENTES. LOS PÉ;PTIDOS UNIDOS A MOLÉ;CULAS DEL COMPLEJO MAYOR DE HISTOCOMPATIBILIDAD (MHC), O LOS P&Eacut