QUANTIFICATION DU FACTEUR DE CROISSANCE INSULINOMIMÉTIQUE I ET DU FACTEUR DE CROISSANCE INSULINOMIMÉTIQUE II AVEC UNE SPECTROMÉTRIE DE MASSE À HAUTE RÉSOLUTION
Methods are provided for determining the amount of an IGF-I and/or IGF-II protein in a sample using high resolution / high accuracy mass spectrometry. The methods generally comprise enriching an IGF-I and/or IGF-II protein in a sample, ionizing an IGF-I and/or IGF-II protein from the sample to generate IGF-I and/or IGF-II protein ions, and determining the amount of IGF-I and/or IGF-II protein ions with high resolution / high accuracy mass spectrometry.