EUDES, FRANCOIS,SINGH, JASWANT,RAJAPAKSHA, KOSALA,ANZAR, MUHAMMAD,ADAMS, GREGG P.
申请号:
CA3085022
公开号:
CA3085022A1
申请日:
2018.12.03
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
This disclosure provides a preserving composition comprising a cholesterol: carrier complex, optionally a cholesterol: cyclodextrin complex (CC complex) and/or a cell permeable antioxidant peptide and a biological buffer and optionally a cryprotectant, wherein the preserving composition is optionally substantially free of animal phospholipid, animal protein and/or animal lipoprotein. The disclosure also provides methods for the use of the preserving composition in cryopreservation of semen or sperm cells. Also provided is a kit comprising the preserving composition having a CC complex, a biological buffer, a cryoprotectant, a carbohydrate, a pH stabilizer, an antibiotic or antibiotic cocktail and/or a cell permeable anti-oxidant peptide.