Ying Wang;Stevan W. Djuric;Frauke Pohlki;Wilfried Braje;Ana-Lucia Relo;Irini Akritopoulou-Zanze;Jason T. Brewer;Bhadra Shelat
发明人:
Ying Wang,Jason T. Brewer,Irini Akritopoulou-Zanze,Stevan W. Djuric,Bhadra Shelat,Frauke Pohlki,Wilfried Braje,Ana-Lucia Relo
申请号：
US12765034
公开号：
US08518933B2
申请日:
2010.04.22
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present application relates to 1,2,3,4,4a,5,6,7-octahydropyrazino[1,2 -a][1,4]benzodiazepine, 1,2,3,4,4a,5,6,7-octahydropyrazino[1,2-a][1,5]benzodiazepine, 2,3,4,4a,5,6,7,11b-octahydro-1H-pyrido[3,4-d][2]benzazepine, 1,2,3,4,4a,5,6,7 -octahydropyrazino[1,2-a][1]benzazepine, 1,2,3,4,4a,5-hexahydro-7H-pyrazino[1,2 -a][4,1]benzoxazepine, and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[2,1-d][1,5]benzoxazepine, and 5,6,7,7a,8,9,10,11-octahydropyrazino[1,2-d]pyrido[3,2-b][1,4]diazepine derivatives of formula (I)wherein R1, R2, R3, R4, R5, R6, X1, X2, X3, X4, Y1, Y2, and Y3 are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating disease conditions using such compounds and compositions, and methods for identifying such compounds.
