The environmentally-controlled security enclosure for plant material is adapted for use with a plant. The environmentally-controlled security enclosure for plant material is an environmentally-controlled space within which a plant may be grown, stored, and secured. The environmentally-controlled security enclosure for plant material comprises an inner housing, an environmental system, an internal frame, an outer frame, and a control system. The plant is maintained within the inner housing. The environmental system controls the environmental conditions within the inner housing. The internal frame is a framework upon which the inner housing, the environmental system, and the control system are mounted. The outer frame is an exterior shell within which the internal frame, the inner housing, the environmental system and the control system are contained.