The present invention is directed to a pharmaceutical composition comprising rebamipide having a mean particle size of less than 500 nm, a dispersing agent, and a viscosity enhancing agent wherein the viscosity enhancing agent has no aggregative action for the rebamipide particles, which is used as a gargle or a liquid preparation for swish and swallow comprising rebamipide for preventing and/or treating stomatitis caused by radiotherapy.本發明係針對用於預防及/或治療由於放射治療所導致的口腔炎之醫藥組成物,係包括平均粒徑小於500 nm之瑞巴派特、分散劑及黏度增加劑,其中,該黏度增加劑與該瑞巴派特粒子間無凝集作用,且係用於作為可漱口及吞嚥之漱口水或液體製劑。
