#$%^&*AU2020101537A420200903.pdf#####ABSTRACT The invention discloses a probiotic and its application in gastric injury, belonging to the technical field of microorganisms. The Lactobacillus plantarum HFY09 belongs to the lactic acid bacteria (LAB), and the preservation number is CGMCC No. 16633; This invention adopts a hydrochloric acid/ethanol acute gastric injury model to evaluate the preventive effect of Lactobacillus plantarum HFY09 on gastric injury; The results showed that HFY09 could inhibit gastric juice secretion, maintain the normal pH value of gastric acid, reduce the damage area of gastric mucosa, inhibit apoptosis of gastric mucosal epithelial cells, and play a biological role, which is positively correlated with concentration. HFY09 can be used in the production of probiotics or functional foods, which provides theoretical basis for its further development and utilization.Norml Modecl LB Rariitidjinc EFY09-H HFY09-I, Figure1I