CAULFIELD, THOMAS J.,SMRCINA, MARTIN,THORPE, DAVID S.,WIRE, WILLIAM,ZHAO, JIANHONG,CLEMENS, JENNIFER,FRANCIS, ROBERT S.,FREED, BRIAN S.,JOHN, STANLY,LE, TIEU-BINH,PEDGRIFT, BRIAN,RAMOS, ANTONIO D.,ROS
申请号：
MYPI 20094880
公开号：
MY154462A
申请日:
2008.06.04
申请国别(地区):
MY
年份:
2015
代理人:
摘要：
The present invention relates to novel compounds of the formula Ia: in any of its stereoisomers forms or a mixture of stereoisomeric form in any ratio, or a physiologically acceptable salt thereof, wherein the substituents are as described herein. The inventive compounds have CXCR5 inhibitory activity, and are particularly useful in treating or preventing various inflammatory diseases, such as rheumatoid arthritis, multiple sclerosis, lupus, Crohn's Disease, associated with the modulation of the human CXCR5 receptor.
