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Nowe reagenty i sposób sprzęgania cząsteczek biologicznych
专利权人:
Polytherics Limited
发明人:
GODWIN, ANTHONY
申请号:
PL09784718
公开号:
PL2326349T3
申请日:
2009.07.17
申请国别(地区):
PL
年份:
2015
代理人:
摘要:
The invention relates to a process for the conjugation of a molecule containing a thiol or amino group to a polymer, which comprises reacting said molecule with a compound of the general formula: €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ X-[Q-W-(CH=CH) n -CH=CH 2 ] m €ƒ€ƒ€ƒ€ƒ€ƒ(V) in which X represents a polymer; Q represents a linking group; W represents a keto group or an ester group -O-CO-; n represents 0 or an integer of from 1 to 4; and m represent an integer of from 1 to 8. The invention also relates to a compound of the general formula €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ X-[NH-CO-Ar-W-(CH=CH) n -CH=CH 2 ] m €ƒ€ƒ€ƒ€ƒ€ƒ(Va) in which X, W, n and m have the meanings given above; and Ar represents an unsubstituted or substituted aryl group.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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