KIM, SUNG WUK,JUN, SUNG SOO,PARK, SEUNG KOOK,KIM, SONG YOUNG,KIM, EUN SUN,JEONG, JAE KAP,KIM, HA NA,SONG, YEON JUNG
申请号:
EP11851725
公开号:
EP2657252A4
申请日:
2011.12.21
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Provided is a modified human tumor necrosis factor receptor-1 polypeptide or a fragment thereof that binds to a tumor necrosis factor in vivo or ex vivo. The modified human tumor necrosis factor receptor-1 polypeptide or fragment exhibits improved ability to bind tumor necrosis factor and resistance to proteases.