Anca CATRINA,Camilla SVENSSON,Lars KLARESKOG,Vivianne MALMSTROM
申请号：
US15393335
公开号：
US20170105971A1
申请日:
2016.12.29
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Bone loss and/or pain associated with an elevated activation of osteoclasts is prevented, treated and/or alleviated by the administration of an effective amount of a compound capable of inhibiting the activity of a peptidylarginine deiminase (PAD) enzyme. Methods and compounds for this use are disclosed, as well as diagnostic methods, kits, and a method for identifying compounds effective to prevent, treat and/or alleviate bone loss and/or pain.
