BOITANO, ANTHONY,COOKE, MICHAEL,PAN, SHIFENG,SCHULTZ, PETER G.,TELLEW, JOHN,WAN, YONGQIN,WANG, XING
申请号：
CA2740589
公开号：
CA2740589C
申请日:
2009.10.29
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The invention relates to a cell population comprising expanded hematopoieticstem cells (HSCs)and its use in autologous or allogeneic transplantation for the treatment ofpatients with inheritedimmunodeficient and autoimmune diseases and diverse hematopoietic disorders toreconstitute thehematopoietic cell lineages and immune system defense.The present invention further relates to compounds and compositions, and theprocess forexpanding the number of CD34+ cells for transplantation. The compounds usefulfor expandingthe number of CD34+ cells are of Formula 1a:(see formula 1a)wherein the variables are as described herein.
