Pharmaceutical formulations of azol for parenteral administration and methods for the preparation and use thereof as a treatment for diseases sensitive to azol compounds
Benigno C. Valdez;Jeffrey Tarrand;Borje S. Andersson
发明人:
ANDERSSON, Borje S.,TARRAND, Jeffrey,VALDEZ, Benigno C.
申请号：
ES11849408
公开号：
ES2565353T3
申请日:
2011.12.16
申请国别(地区):
ES
年份:
2016
代理人:
摘要：
A pharmaceutical composition suitable for parenteral administration, comprising an azol pharmaceutical agent and a first solvent, said first solvent comprising a) an alcohol component selected from benzyl alcohol and / or acidified ethanol, and b) polyethylene glycol (PEG), wherein the The azol agent is dissolved in said first solvent, the composition being essentially free of non-ionic surfactants and comprising less than 5% water.Una composicion farmaceutica adecuada para administracion parenteral, que comprende un agente farmaceutico de azol y un primer disolvente, comprendiendo dicho primer disolvente a) un componente de alcohol seleccionado entre alcohol bencilico y/o etanol acidificado, y b) polietilenglicol (PEG), en donde el agente de azol se disuelve en dicho primer disolvente, estando la composicion esencialmente libre de tensioactivos no ionicos y comprendiendo menos de un 5 % de agua.
