TURNER, BRIAN CURTIS,REFAELI, YOSEF,BIRD, GREGORY A.
申请号：
EP14778538
公开号：
EP2970898A4
申请日:
2014.03.11
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
The present disclosure relates to the production of red blood cells from hematopoietic stem cells, by differentiating such cells in the presence of a protein that induces cell survival and proliferation. It also discloses a method for extending the half-life of a population of mature red blood cells in vitro comprising maintaining a population of such red blood cells in a culture media comprising an exogenous polypeptide comprising one or more Bcl-2 homology domains.
