To provide a device and a method for plugging an opening in a biological tissue.A delivery device for carrying a living tissue connection device, the delivery device comprising a shaft, a needle, a second jaw, and a retention mechanism, the shaft having a first jaw Wherein the distal tip and the first jaw share a shaft lumen extending both longitudinally and opening at the distal tip of the first jaw, the needle being in communication with the needle lumen And a needle tip extending within the shaft lumen and slidable therein into a protruding position wherein the protruding position is such that the needle point passes through a distal tip of the first jaw to a predetermined Wherein the needle lumen protrudes to a maximum protruding length retracted position and wherein the needle lumen is sized to accommodate a plurality of suture threaded tissue connecting members and the second jaw is distal Side end and / or a first jaw part To a jaw actuator configured to freely drive the second jaw between a closed position close to the first jaw and an open position in which the second jaw is pivoted away from the first jaw Wherein the retention mechanism is provided at a distal tip of the second jaw and when the second jaw is in the closed position and the most distal tissue while the needle is in the retracted position Wherein the connecting member is configured to retain the connecting member of the most distal tissue when the connecting member partially protrudes from the distal tip of the first jaw.BACKGROUND OF THE INVENTION【課題】生体組織において開口を塞ぐためのデバイス及び方法を提供すること。【解決手段】生体組織接続デバイスを運ぶための送達デバイスであって、シャフトと、針と、第2顎部と、保持機構とを備え、前記シャフトは、その遠位側の先端において第1顎部と接続され、この遠位側の先端と第1顎部とは両方とも長手方向に延び且つ第1顎部の遠位側の先端において開くシャフトルーメンを共有し、前記針は、針ルーメンと針先とを備え、前記シャフトルーメンの内部で延長し且つ突出位置までその中でスライド可能で、前記突出位置とは、前記針先が第1顎部の遠位側の先端を通って所定の最大突出長分引き込み位置まで突出するものであって、且つ前記針ルーメンが複数の、縫合糸に通された組織接続部材を収容する大きさであり、第2顎部は、前記シャフトの遠位側の先端及び/又は第1顎部と旋回可能に接続され且つ第1顎部に近接する閉位置と第2顎部が第1顎部から旋回して離れる開位置との間で第2顎部を自由に駆動させるように構成される顎部アクチュエータに接続され、前記保持機構
