Eric Connor,Kalpesh Biyani,Scott Hecker,Inez Lees,Paul Mansky,YongQi Mu,Faleh Salaymeh,Hongmin Zhang,David E. Bergbreiter,Grace Huynh,Michael James Cope,Elizabeth Goka,Angela Lee,Deidre Madsen,Jun Sha
申请号:
US15601291
公开号:
US20170258825A1
申请日:
2017.05.22
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides crosslinked amine polymers effective for binding and removing bile salts from the gastrointestinal tract. These bile acid binding polymers or pharmaceutical compositions thereof can be administered to subjects to treat various conditions, including hypercholesteremia, diabetes, pruritus, irritable bowel syndrome-diarrhea (IBS-D), bile acid malabsorption, and the like.