BENGHEZAL, MOHAMMED,DEBOWSKI, ALEKSANDRA WERONIKA,SEHNAL, MIRIAM,DIEYE, YAKHYA,PARK, SE-HOON,MARSHALL, BARRY
申请号:
CA2829154
公开号:
CA2829154A1
申请日:
2012.03.09
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to a gene expression and eradication system for Helicobacter pylori (H. pylori). In particular, the present invention relates to a genetic construct comprising, in the 5'-3' direction: (a) a promoter sequence and (b) a DNA sequence of interest, wherein the promoter sequence comprises a polynucleotide sequence capable of regulating expression of the DNA sequence of interest in Helicobacter pylori and wherein said promoter sequence is modified to comprise a tetracycline (tet) operator sequence.