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TUNABLY CROSSLINKED HYALURONIC ACID COMPOSITIONS
专利权人:
INC.;ALLERGAN
发明人:
TEZEL, AHMET,STROUMPOULIS, DIMITRIOS
申请号:
NZ58303108
公开号:
NZ583031A
申请日:
2008.07.24
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
A process for the preparation of crosslinked hyaluronic acid hydrogel suitable for soft tissue augmentation is disclosed, wherein said process comprises:(a) hydrating sodium hyaluronate fibers in a sodium hydroxide solution to produce hydrated sodium hyaluronate fibers; and (b) contacting the sodium hyaluronate fibers with a polyethylene glycol-based epoxide crosslinking agent to create a crosslinked hyaluronic acid hydrogel suitable for soft tissue augmentation, wherein the polyethylene glycol-based epoxide crosslinking agent has two to six reactive groups for linking to hyaluronic acid side chains, preferably the polyethylene glycol-based epoxide crosslinking agent is tetrafunctional.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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