#$%^&*AU2011253822A120120112.pdf#####ABSTRACT (S)- 1-(4-Chloro-5-isoquinolinesulfonyD-3-(methylamino)pyrrolidine monohydrochloride and a crystal thereof, and a crystal of the aforementioned monohydrochloride having a major peak or peaks at one or more positions selected from the group consisting of positions where 20s are about 13.90, 21.50, 21.7*, 22.4, 22.8*, 24.5" and 35.00 in a powder X-ray diffraction spectrum, which have excellent properties as active ingredient of a medicament for prophylactic and/or therapeutic treatment of glaucoma and the like. 37