KANIA, ROBERT STEVEN,BENDER, STEVEN LEE,BORCHARDT, ALLEN J.,BRAGANZA, JOHN F.,CRIPPS, STEPHAN JAMES,HUA, YE,JOHNSON, MICHAEL DAVID,JR. JOHNSON, THEODORE OTTO,LUU, HIEP THE,PALMER, CYNTHIA LOUISE,REICH
申请号：
HU0202490
公开号：
HU228502B1
申请日:
2000.06.30
申请国别(地区):
HU
年份:
2013
代理人:
摘要：
Indazole compounds that modulate and/or inhibit the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer and other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.
