Use of substituted quinoline derivatives for the treatment of drug-resistant mycobacterial diseases

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专利权人:

ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ

发明人:

ケンラート・ヨゼフ・ロデビーク・マルセル・アンドリース,ヨゼフ・フラン・エリザベータ・バン・ゲステル

申请号：

JP2012152373

公开号：

JP5675718B2

申请日:

2012.07.06

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

The present invention relates to the use of a substituted quinoline derivative for the preparation of a medicament for the treatment of an infection with a drug resistant Mycobacterium strain wherein the substituted quinoline derivative is a compound according to Formula (Ia) or Formula (Ib) the pharmaceutically acceptable acid or base addition salts thereof, the stereochemically isomeric forms thereof, the tautomeric forms thereof and the N-oxide forms thereof. Also claimed is a composition comprising a pharmaceutically acceptable carrier and, as active ingredient, a therapeutically effective amount of the above compounds and one or more other antimycobacterial agents.

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