Hyung Kyu LIM,Jong Soo LEE,Dae Jin KIM,Sung Min BAE,Sung Youb JUNG,Se Chang KWON
申请号:
US15129897
公开号:
US20170128589A1
申请日:
2015.03.31
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to a method for improving the solubility of a physiologically active protein or peptide compared to that of a physiologically active protein or peptide which is not conjugated to an immunoglobulin Fc fragment, in which the method comprises conjugating the physiologically active protein or peptide to an immunoglobulin Fc fragment; and a composition for improving the solubility of a physiologically active protein or peptide, comprising an immunoglobulin Fc fragment, in which the composition improves the solubility compared to a composition without an immunoglobulin Fc fragment.