Develop the symptoms of anxiety or the present invention provides a method for effective prevention or treatment of patients at risk, and effective treatment with agents that inhibit the specific binding to the NMDA receptor and PSD95 in which But it is administered to the patient.本発明は不安の症状を発症する若しくはリスクのある患者の治療又は効果的な予防の方法を提供し、そこではPSD95とNMDA受容体との特異的結合を阻害する薬剤を用いた効果的な治療が患者に投与される。