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Związki sulfonamidowe mające działanie antagonistyczne dla TRPMS
专利权人:
Mitsubishi Tanabe Pharma Corporation
发明人:
TSUZUKI YASUYUKI,SAWAMOTO DAISUKE,SAKAMOTO TOSHIAKI,KATO TAKU,NIWA YASUKI,AWAI NOBUMASA
申请号:
PL12712777
公开号:
PL2686302T3
申请日:
2012.03.15
申请国别(地区):
PL
年份:
2017
代理人:
摘要:
Sulfonamide compounds having TRPM8 antagonistic activity are provided. A sulfonamide compound of formula (I) or a pharmaceutically acceptable salt thereof, or a prodrug thereof: (I) wherein Ring A is bicyclic aromatic heterocycle comprised of (a) pyridine is condensed with benzene; or (b) pyridine is condensed with monocyclic aromatic heterocycle, and Ring A binds to a sulfonylamino moiety on a carbon atom adjacent to a nitrogen atom of the pyridine ring constituting Ring A, Ring B is (a) monocyclic or bicyclic aromatic hydrocarbon; (b) monocyclic or bicyclic alicyclic hydrocarbon; (c) monocyclic or bicyclic aromatic heterocycle; or (d) monocyclic or bicyclic non-aromatic heterocycle, Ring C is (a) benzene; or (b) monocyclic aromatic heterocycle, and other symbols are the same as defined in the specification.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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