Temperature variations in a patients body can lead to inaccurate glucose readings. To compensate for changes in temperature, the temperature at a glucose sensing site can be sensed using a thermocouple. A compensated glucose level can be determined based on the temperature and the sensed glucose level. A glucose sensing device is described that includes a glucose sensor having a working electrode and a thermocouple having a junction positioned proximate the working electrode, with both the glucose and temperature sensors including the same metals.
