A probe (70) for measuring tissue comprising a fiber optic probe having a proximal end and a distal end, a delivery optical fiber (76) in the probe that delivers light onto tissue, a collection optical fiber (72) in the probe that collects Raman scattered radiation from tissue and an optical system on the distal end of the probe, the optical system being optically coupled to a distal end of the delivery optical fiber (76) and a distal end of the collection optical fiber (72)r.