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PLK INHIBITOR SALTS
专利权人:
Riccardo Frigerio;Italo Beria;Annalisa Airoldi;Massimo Zampieri;Ilaria Candiani
发明人:
Massimo Zampieri,Italo Beria,Annalisa Airoldi,Ilaria Candiani,Riccardo Frigerio
申请号:
US13387051
公开号:
US20120157468A1
申请日:
2010.07.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to novel crystalline, water-soluble salts of a plk inhibitor. Such crystal salts are for example L-tartrate, succinate, phosphate, mesylate, maleate, L-malate, hydrochloride, fumarate (half mole of counterion), fumarate, citrate (half mole of counterion), benzenesulfonate and L-aspartate (half mole of counterion). New crystal forms of the base as well as solvates and hydrates of such new salt forms, a process for their preparation, their utility in therapy and to the pharmaceutical compositions containing them are also claimed and described in the present application.
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中国工程科技知识中心
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