This invention provides: 1) a method of treating androgen deprivation induced osteoporosis bone fractures loss of bone mineral density (BMD) and/or hot flashes in a male subject suffering from prostate cancer 2) a method of preventing androgen deprivation induced osteoporosis bone fractures loss of bone mineral density (BMD) and/or hot flashes in a male subject suffering from prostate cancer 3) a method of suppressing or inhibiting androgen deprivation induced osteoporosis bone fractures loss of bone mineral density (BMD) and/ or hot flashes in a male subject suffering from prostate cancer and 4) a method of reducing the risk of developing androgen deprivation induced osteoporosis bone fractures loss of bone mineral density (BMD) and/ or hot flashes in a male subject suffering from prostate cancer by administering to the subject a pharmaceutical composition comprising cis clomiphene or a pharmaceutically acceptable salt thereof.
