George R. Ehring,Ellen Chao,Herman Ng,Hau Ton,Jia Chian Li,Joseph S. Adorante,Michael S. Garst,Howard B. Rind,Mark R. Hansen,Alfred Arthur Avey, Jr.,Lloyd Jay Dolby,Shervin Esfandiari,Vivian R. MacKen
申请号:
US13727860
公开号:
US08859780B2
申请日:
2012.12.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention is directed to a compound of Formula Ior a pharmaceutically acceptable salt thereof; wherein R, R1, R2, R3, R4, m, and n are as defined herein, to pharmaceutical compositions comprising said compound, and to methods of treating diseases or conditions mediated by elevated persistent sodium current, such as an ocular disorder, multiple sclerosis, seizure disorder, and chronic pain.