Armelle Marie-Laudine JANIN,Philip Alexander Macfaul,Rachel Marie Pugh,Emily Jane Roberts,Ian Alun Nash
申请号：
US14024797
公开号：
US20140045895A1
申请日:
2013.09.12
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A pharmaceutical depot comprising (i) 5-fluoro-2-[[(1S)-1-(5-fluoro-2-pyridyl)ethyl]amino]-6-[(5-isopropoxy-1H-pyrazol-3-yl)amino]pyridine-3-carbonitrile, or a pharmaceutically-acceptable salt thereof, as a pharmaceutical agent (PA) and (ii) a polymer which degrades to create an acidic microclimate, wherein the PA is released from the polymer upon polymer degradation.
