PURRO, NORBERT,SMYTH, MARK,GOLDMAN, ERICK,WIRTH, DAVID D.
申请号：
CA2991994
公开号：
CA2991994A1
申请日:
2013.06.03
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Described herein is the Bruton's tyrosine kinase (Btk) inhibitor1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, includingcrystalline forms, solvates and pharmaceutically acceptable salts thereof.Also disclosed arepharmaceutical compositions that include the Btk inhibitor, as well as methodsof using the Btkinhibitor, alone or in combination with other therapeutic agents, for thetreatment of autoimmunediseases or conditions, heteroimmune diseases or conditions, cancer, includinglymphoma, andinflammatory diseases or conditions.
