Vesci, Loredana,De Santis, Rita,Milazzo, Ferdinando Maria,Giannini, Giuseppe,Taddei, Maurizio,Faltoni, Valentina,Petricci, Elena
申请号：
AU2018241840
公开号：
AU2018241840A1
申请日:
2018.03.27
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
The present invention relates to novel Histone Deacetylase Inhibitors (HDACi)- based antibody drug conjugates particularly with antibodies directed to ErbB1, ErbB2 and ErbB3 receptors, pharmaceutical compositions comprising said antibodies as well as to their use in the treatment of cancer or tumor and other diseases where a modulation of one or more histone deacetylase isoforms can be effective for therapeutic interventions.
