SACCHETTINI, James, C.,AGGARWAL, Anup,PARAI, Maloy, K.
申请号:
EP16783946
公开号:
EP3285873A4
申请日:
2016.04.22
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Novel bacterial inhibitors comprising benzofuran derivatives, and methods of bacterial inhibition using the inhibitors are disclosed. The inhibitors may inhibit, for example, mycobacteria, including M. tuberculosis, by inhibition of the Pksl3 enzyme. The inhibitors cmat exhibit potent whole cell and in vivo efficacy against M. tuberculosis.