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DOSAGE REGIMEN D'ANTICORPS ANTI-ALPHA4BÊTA7
专利权人:
Inc.;Millennium Pharmaceuticals
发明人:
申请号:
EP18150968.8
公开号:
EP3329965A1
申请日:
2012.05.02
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Antibody formulations are described comprising a mixture of a non-reducing sugar, an anti-α4β7 antibody and at least one amino acid. The disclosed formulations have improved stability, reduced aggregate formation, and may retard degradation of the anti-α4β7 antibody therein or exhibit any combinations thereof. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-α4β7 antibody in vivo.
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中国工程科技知识中心
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