Lorena Lerner,Sandra Abbott,Ailin Bai,Ting Chen,Maria I. Chiu,Qing Liu,Laura Poling,Nianjun Tao,Solly Weiler,Zhigang Weng,William M. Winston, Jr.,Jeno Gyuris
申请号:
US14863870
公开号:
US09725505B2
申请日:
2015.09.24
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Monoclonal antibodies that bind and inhibit the activity of human GDF15 are disclosed. The antibodies can be used to treat body weight loss, including cachexia, associated with the over-expression of human GDF15.