ANDREW ALAN SHAW,GLENN ALLEN REDELMAN,SARAT C. CHATTARAJ
申请号：
BR112014032579
公开号：
BR112014032579A2
申请日:
2012.06.25
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
abstract: title fenofibrate formulation various fenofibrate compositions include a plurality of first granules having a high bioavailability in vivo, and a plurality of second granules having a low bioavailability in vivo. the first granules may comprise fenofibrate, from 0.3% to 10% by weight of the first granules of a first surfactant, and a first water soluble or dispersible cellulose derivative, and the second granules may comprise fenofibrate, from 0% to 0.25% by weight of the second granules of a second surfactant, and a second water soluble or water dispersible derivative cellulose. ________________________________________________________________________ Translation of the abstract patent summary: "fenofibrate formulation". These are various fenofibrate compositions that include a plurality of first granules that have a high bioavailability in vivo and a plurality of second granules that have a low bioavailability in vivo. the first granules may comprise 0.3% to 10% by weight fenofibrate of the first granules of a first surfactant and a first water-soluble or water-dispersible cellulose derivative and the second granules may comprise 0% fenofibrate 0.25% by weight of the second granules of a second surfactant and a second water-soluble or water-dispersible cellulose derivative.abstract: title fenofibrate formulation various fenofibrate compositions include a plurality of first granules having a high bioavailability in vivo, and a plurality of second granules having a low bioavailability in vivo. the first granules may comprise fenofibrate, from 0.3% to 10% by weight of the first granules of a first surfactant, and a first water soluble or water dispersible cellulose derivative, and the second granules may comprise fenofibrate, from 0% to 0.25% by weight of the second granules of a second surfactant, and a second water soluble or water dispersible cellulose derivative. ________________________________________________________________________ tradução do resumo
