GLYCOSYLATED FORM OF ANTIGENIC GLP-1 ANALOGUE

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专利权人:

OTSUKA CHEMICAL CO.; LTD.

发明人:

KAJIHARA, YASUHIRO,TSUJI, TAKASHI,NAMBU, YURI,ISHII, KAZUYUKI,YOSHIDA, KENTA,TEZUKA, KATSUNARI

申请号：

SG2012029476

公开号：

SG180488A1

申请日:

2010.10.25

申请国别(地区):

SG

年份:

2012

代理人:

摘要：

Disclosed is a GLP-1 analogue which is obtained by ameliorating a highly antigenic GLP-1 analogue so that the GLP-1 analogue has reduced antigenicity without being lowered in the blood glucose suppressing activity.Specifically disclosed is a glycosylated form of an antigenic GLP-1 analogue, which has GLP-1 activity and is obtained by substituting at least one amino acid of an antigenic GLP-1 analogue with a glycosylated amino acid.

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