An automated switch and driver for an open biased spring-based multiple purpose end effector of a medical instrument to be used by a single operator without assistance for biopsy, clipping, clamping, grasping, snaring, cutting, dissecting or other operative functions with electrical connections for cautery or hot biopsy used independently or combined with a rigid or flexible endoscope of any size. The driver mechanism may be a spring(s), gear(s), electrical solenoid or motor, air or hydraulic pressure activated piston or a combination thereof. Automated action may be initiated by voice, hand or foot switch. The switch and driver mechanism may be disposable, attached to or separable from the operative instrument or permanently attached to be reusable. The automated end effector instrument may be combined with or incorporated into an endoscope.