A monomer composed of 6-((7s) -7-hydroxy-6,7-dihydro-5h-pirrolo [1,2-c] imidazol-7-il]-N-methyl-2-naftamida, D-Manitol and alkaline metal salts selected from magnesium and calcium silicate； and a stabilizer of the compound for the prevention and/or silicate L Tumor treatment.
The present invention provides a solid preparation wherein variation in weight is suppressed, a solid preparation wherein the active ingredient is stabilized, and a stabilization method thereof. A solid preparation containing (1) an active ingredient, (2) D-mannitol and (3) an alkaline earth metal salt selected from magnesium aluminometasilicate and calcium silicate. A method of stabilizing the. active ingredient, including adding an alkaline earth metal salt selected from magnesium aluminometasilicate and calcium silicate.PREPARACION SOLIDA QUE COMPRENDE 6-((7S)-7-HIDROXI-6,7-DIHIDRO-5H-PIRROLO[1,2-C]IMIDAZOL-7-IL)-N-METIL-2-NAFTAMIDA, D-MANITOL Y UNA SAL DE METAL ALCALINOTERREO SELECCIONADA DE ALUMINOMETASILICATO DE MAGNESIO Y SILICATO DE CALCIO； Y METODO DE ESTABILIZACION DEL COMPUESTO, UTIL PARA LA PREVENCION O EL TRATAMIENTO DE TUMORES.
