MATHIESEN, IACOB,TJELLE, ELISABETH TORUNN,KJEKEN, RUNE,RABUSSAY, DIETMAR,LIN, FENG
申请号：
EP07840065
公开号：
EP2091558A4
申请日:
2007.11.16
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
Disclosed are methods of enhancing immune responses. Such methods involve the administration of vaccine compositions to different tissues to elicit an enhanced immune response. The enhanced response arises from the vaccination and boosting route of administration in two separate patient tissues, for example, by first administering a priming vaccination into skin and later administering a boost vaccination in muscle. In each case, priming and boosting, the administration of the vaccine composition is preferably carried out using contemporaneous electroporation-assisted delivery of the antigenic agent.
